ADAMDEC1 Is a Metzincin Metalloprotease with Dampened Proteolytic Activity
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منابع مشابه
Activation and Proteolytic Activity of the Treponema pallidum Metalloprotease, Pallilysin
Treponema pallidum is a highly invasive pathogen that undergoes rapid dissemination to establish widespread infection. Previous investigations identified the T. pallidum adhesin, pallilysin, as an HEXXH-containing metalloprotease that undergoes autocatalytic cleavage and degrades laminin and fibrinogen. In the current study we characterized pallilysin's active site, activation requirements, cel...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.m113.474536